Synthesis, Characterization and Antibacterial Efficacy of Catharanthus roseus and Ocimum tenuiflorum-Mediated Silver Nanoparticles: Phytonanotechnology in Disease Management

Nanotechnology is an emerging multidisciplinary field that has the potential to offer solutions pharmaceutical challenges starting from drug delivery therapeutic applications. The plant-mediated method eco-friendly and most inexpensive of various techniques used synthesize nanoparticles (NPs). In this study, silver (Ag) NPs have been successfully synthesized using leaf extract Catharanthus roseus Ocimum tenuiflorum. X-ray diffraction revealed average crystalline size 19.96 21.42 nm for C. O. tenuiflorum-mediated Ag NPs, respectively. Further, shape, size, elemental composition were analyzed a scanning electron microscope, transmission microscope (TEM), energy-dispersive spectral technique. TEM study spherical/spheroidal-shaped formed between 10–48 with 17–55 Both inhibited Escherichia coli Bacillus subtilis, where effect was more prominent against E. (MIC 3.90 ± 0 µg/mL) tenuiflorum NPs. Mechanistic insights antibacterial activity also highlighted, might be attributed diverse mode action surface functionalized phytoconstituents